Recorded on: April 4, 2023
This webinar is brought to you by the Health & Nutrition Division of AOCS.
Organizer: Dr. Rinat Ran-Ressler, Principal Scientist, Nutrition, Technology and Innovation, NPTC, Nestlé Health Science
Improving PUFA Metabolism Analytics & Recognizing The Role of Omega-3 SDA & ETA:
How New Research Is Challenging ‘Inefficiency’ in DHA Biosynthesis & ‘Insufficiency’ From Plant-Based Sources
Compound-specific isotope analysis for the study of dietary intake and metabolism of polyunsaturated fatty acids
Dr. Adam Metherel
This presentation will focus on nutritionally applications of compound-specific isotope analysis (CSIA) by gas chromatography combustion isotope ratio mass spectrometry (GC/C/IRMS). Focus will be on how small variations in the carbon-13 content of dietary polyunsaturated fatty acids (PUFA) can be used as a tool for investigating various questions related to PUFA metabolism.
The Importance of Under-Studied Omega-3 SDA & ETA
Greg Cumberford
This presentation will discuss emerging health findings related to plant-based stearidonic acid (SDA, C18:4n-3) and its metabolite eicosatetraenoic acid (ETA, C20:4n-3). Dietary SDA by-passes a key rate-limiting step in n-3 PUFA synthesis, facilitating more efficient n-3 PUFA accrual and/or biosynthesis in mammals than from dietary ALA sources. ETA is a substrate for lipoxygenase and cyclooxengenase enzymes and one of its oxylipins has recently been recognized to possess anti-inflammatory activity. SDA and ETA have important implications for improving health outcomes from a more diverse range of dietary omega-3 sources.