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Improving PUFA Metabolism Analytics & Recognizing The Role of Omega-3 SDA & ETA
Closed
Date:
April 4, 2023
Time:
10:00 AM - 11:00 AM

Recorded on: April 4, 2023

This webinar is brought to you by the Health & Nutrition Division of AOCS.

Organizer: Dr. Rinat Ran-Ressler, Principal Scientist, Nutrition, Technology and Innovation, NPTC, Nestlé Health Science

Improving PUFA Metabolism Analytics & Recognizing The Role of Omega-3 SDA & ETA:
How New Research Is Challenging ‘Inefficiency’ in DHA Biosynthesis & ‘Insufficiency’ From Plant-Based Sources

Compound-specific isotope analysis for the study of dietary intake and metabolism of polyunsaturated fatty acids
Dr. Adam Metherel
 
This presentation will focus on nutritionally applications of compound-specific isotope analysis (CSIA) by gas chromatography combustion isotope ratio mass spectrometry (GC/C/IRMS). Focus will be on how small variations in the carbon-13 content of dietary polyunsaturated fatty acids (PUFA) can be used as a tool for investigating various questions related to PUFA metabolism.
 
The Importance of Under-Studied Omega-3 SDA & ETA
Greg Cumberford

This presentation will discuss emerging health findings related to plant-based stearidonic acid (SDA, C18:4n-3) and its metabolite eicosatetraenoic acid (ETA, C20:4n-3). Dietary SDA by-passes a key rate-limiting step in n-3 PUFA synthesis, facilitating more efficient n-3 PUFA accrual and/or biosynthesis in mammals than from dietary ALA sources. ETA is a substrate for lipoxygenase and cyclooxengenase enzymes and one of its oxylipins has recently been recognized to possess anti-inflammatory activity. SDA and ETA have important implications for improving health outcomes from a more diverse range of dietary omega-3 sources.

About our speakers:
Dr. Adam Metherel is an Assistant Professor in the Department of Nutritional Sciences at the University of Toronto. Following completion of his PhD with Dr. Ken Stark at the University of Waterloo, he trained as a postdoctoral fellow with Certo Labs Inc. and then Dr. Richard...

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